Publications

2025

Helical neural implants for intracerebral drug delivery

Published in: Journal of Neural Engineering

Batoul Khlaifat, Mahmoud Elbeh, Shreya Manjrekar, Seung-Jean Kang, Yusheng Zhang, Parima Phowarasoontorn, Sadaf Usmani, Abdel-Hameed Dabbour, Heba T Naser, Hanan Mohammed, Minsoo Kim, Khalil B Ramadi

Ingestible sensors for redox balance: Bioelectronics

Published in: Nature Electronics

Khalil B Ramadi

Passive intestinal microbiome sampling using an ingestible device with tortuous lattices

Published in: Device

Hanan Mohammed, Sadaf Usmani, Brij Bhushan, Anique Ahmad, Oraib Al-Ketan, Ahmed A Shibl, Maylis Boitet, Devjoy Dev, Heba T Naser, Aashish R Jha, Khalil B Ramadi

Wirelessly Powered Ingestible Capsule for Optical Stimulation of the Gastrointestinal Tract in Rodents

Published in: Advanced Materials Technologies

Mohamed Elsherif, Rawan Badr El‐Din, Zhansaya Makhambetova, Heba T Naser, Maylis Boitet, Rahul Singh, Keonghwan Oh, Revathi Sukesan, Sohmyung Ha, Khalil B Ramadi

Based Microfluidic Assay for Gingipain Detection Using Fluorescent Quantum Dots

Conference: 2025 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)

Pavithra Sukumar, Mahmoud Elbeh, Zuzanna Bak, Mohammed Abdelhameed, Khalil B Ramadi, Mohammad A Qasaimeh

Single-step, one-pot, catalyst-free upcycling of polyethylene terephthalate into biphasic carbon dots and high-purity terephthalic acid

Published in: Green Chemistry

Kevin Brian, Mahmoud Elbeh, Mohammed Abdelhameed, Batoul Khlaifat, Fatma Alrebh, Liaqat Ali, Batool Abedrabbo, Brijith Thomas, Khalil B Ramadi

2024

Carbon quantum dot fluorescent stickers for biochip authentication

Conference: 2024 IEEE 33rd Asian Test Symposium (ATS)

Navajit Singh Baban, Mohammed Abdelhameed, Mahmoud Elbeh, Khalil B Ramadi, Yong-Ak Song, Sukanta Bhattacharjee, Ramesh Karri, Krishnendu Chakrabarty

Making hospitals innovative: Macro-level policy to sustain micro-innovations in healthcare

Published in: Healthcare Management Forum

Khalil B Ramadi, Saakshi More, Anshuman Shaji

An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut

Published in: Nature communications

Kewang Nan, Kiwan Wong, Dengfeng Li, Binbin Ying, James C McRae, Vivian R Feig, Shubing Wang, Ningjie Du, Yuelong Liang, Qijiang Mao, Enjie Zhou, Yonglin Chen, Lei Sang, Kuanming Yao, Jingkun Zhou, Jian Li, Joshua Jenkins, Keiko Ishida, Johannes Kuosmanen, Wiam Abdalla Mohammed Madani, Alison Hayward, Khalil B Ramadi, Xinge Yu, Giovanni Traverso

Design of Three-Dimensional-Printed Compression Ring for Enhanced Wound Healing of Colorectal Anastomosis to Minimize Dehiscence and Leakage Post Colectomy

Published in: Journal of Medical Devices

Parima Phowarasoontorn, SojaThilini Rajakaruna, Aliha Nisha, Jesper Holter, Oraib Al-Ketan, Carlos Abril Vega, Juan S Barajas-Gamboa, Shadi Al-Bahri, Khalil B Ramadi

Edible electronics to treat the brain

Published in: Science

Khalil B Ramadi

Plasmonic contact lenses based on silver nanoparticles for blue light protection

Published in: ACS Applied Nano Materials

Mohamed Elsherif, Ahmed E Salih, Fahad Alam, Ali K Yetisen, Khalil B Ramadi, Haider Butt

Fiber-optic probes for real-time pH monitoring

Published in: Sensors & Diagnostics

Mohamed Elsherif, Fahad Alam, Ahmed E Salih, Xinyu Wang, Peter R Corridon, Khalil B Ramadi, Haider Butt

2023

Inter-disciplinary collaboration for innovation in gastroenterology

Published in: Nature Reviews Gastroenterology & Hepatology

Khalil B Ramadi

Plasmonics for neuroengineering

Published in: Communications Materials, 2023

NS Susan Mousavi, Khalil B Ramadi, Yong-Ak Song, Sunil Kumar

Shape memory-based gastric motility 3D mapping

Published in: Device

Neil Zixun Jia, Qiyun Gao, Vítor Sencadas, Michelle Zong, Jesse George-Akpenyi, Sylvia E Waft, Johannes LP Kuosmanen, Josh Jenkins, Keiko Ishida, Alison M Hayward, Wiam Abdalla Mohammed Madani, Niora Fabian, George Selsing, Stephanie Owyang, Khalil B Ramadi, Ziliang Kang, Hen-Wei Huang, Giovanni Traverso

Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation

Published in: Science robotics

Khalil B Ramadi, James C McRae, George Selsing, Arnold Su, Rafael Fernandes, Maela Hickling, Brandon Rios, Sahab Babaee, Seokkee Min, Declan Gwynne, Neil Zixun Jia, Aleyah Aragon, Keiko Ishida, Johannes Kuosmanen, Josh Jenkins, Alison Hayward, Ken Kamrin, Giovanni Traverso

Location-aware ingestible microdevices for wireless monitoring of gastrointestinal dynamics

Published in: Nature Electronics

Saransh Sharma, Khalil B Ramadi, Nikhil H Poole, Shriya S Srinivasan, Keiko Ishida, Johannes Kuosmanen, Josh Jenkins, Fatemeh Aghlmand, Margaret B Swift, Mikhail G Shapiro, Giovanni Traverso, Azita Emami

High-yield, one-pot upcycling of polyethylene and polypropylene waste into blue-emissive carbon dots

Published in: Green Chemistry

Mohammed Abdelhameed, Mahmoud Elbeh, Navajit S Baban, Leticia Pereira, Julie Matula, Yong-Ak Song, Khalil B Ramadi

2022

The road ahead for applications of mechanics in drug delivery

Published in: Mechanics Research Communications

Morteza Sarmadi, Siddharth R Krishnan, Khalil B Ramadi, Robert Langer

Machine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors

Published in: Translational Oncology

Max J Cotler, Khalil B Ramadi, Xiaonan Hou, Elena Christodoulopoulos, Sebastian Ahn, Ashvin Bashyam, Huiming Ding, Melissa Larson, Ann L Oberg, Charles Whittaker, Oliver Jonas, Scott H Kaufmann, S John Weroha, Michael J Cima

Respiratory Care Innovation in Times of Crisis

Published in: Journal of Emergency Nursing

Shriya S Srinivasan, Rajib Mondal, Khalil B Ramadi

Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer

Published in: NPJ digital medicine

Khalil B Ramadi, Rhea Mehta, David He, Sichen Chao, Zen Chu, Rifat Atun, Freddy T Nguyen

2021

Pre-emptive innovation infrastructure for medical emergencies: accelerating healthcare innovation in the wake of a global pandemic

Published in: Frontiers in Digital Health

Khalil B Ramadi, Shriya S Srinivasan

Rapid crowdsourced innovation for COVID-19 response and economic growth

Published in: NPJ Digital Medicine

Khalil B Ramadi, Freddy T Nguyen

2020

Electroceuticals in the gastrointestinal tract

Published in: Trends in pharmacological sciences

Khalil B Ramadi, Shriya S Srinivasan, Giovanni Traverso

Simultaneous recording and marking of brain microstructures

Published in: Journal of neural engineering

Khalil B Ramadi, Canan Dagdeviren, Preksha Bhagchandani, Carlos Nunez-Lopez, Min Jung Kim, Robert Langer, Ann M Graybiel, Michael J Cima

A rapidly deployable individualized system for augmenting ventilator capacity

Published in: Science translational medicine

Shriya S Srinivasan, Khalil B Ramadi, Francesco Vicario, Declan Gwynne, Alison Hayward, David Lagier, Robert Langer, Joseph J Frassica, Rebecca M Baron, Giovanni Traverso

Computationally guided intracerebral drug delivery via chronically implanted microdevices

Published in: Cell Reports

Khalil B Ramadi, Ashvin Bashyam, Chris J Frangieh, Erin B Rousseau, Max J Cotler, Robert Langer, Ann M Graybiel, Michael J Cima

Individualized system for augmenting ventilator efficacy (iSAVE): a rapidly deployable system to expand ventilator capacity

Published in: BioRxiv

Shriya Srinivasan, Khalil B Ramadi, Francesco Vicario, Declan Gwynne, Alison Hayward, Robert Langer, Joseph J Frassica, Rebecca M Baron, Giovanni Traverso

2019

Democratizing innovation through grass-roots entrepreneurship: lessons from efforts to address the opioid epidemic in the United States

Published in: TBMJ Global Health

Shriya Srinivasan, Khalil B Ramadi, Andrea Ippolito, Rifat Atun

Health in the Arab world

Published in: The Lancet

Khalil B Ramadi, Rifat Atun

Inhibition of tyrosine-phosphorylated STAT3 in human breast and lung cancer cells by manuka honey is mediated by selective antagonism of the IL-6 receptor

Published in: International journal of molecular sciences

Priyanka Aryappalli, Khadija Shabbiri, Razan J Masad, Roadha H Al-Marri, Shoja M Haneefa, Yassir A Mohamed, Kholoud Arafat, Samir Attoub, Otavio Cabral-Marques, Khalil B Ramadi, Maria J Fernandez-Cabezudo, Basel K Al-Ramadi

Steerable microinvasive probes for localized drug delivery to deep tissue

Published in: Small

Max J Cotler, Erin B Rousseau, Khalil B Ramadi, Joshua Fang, Ann M Graybiel, Robert Langer, Michael J Cima

Health diplomacy through health entrepreneurship: using hackathons to address Palestinian-Israeli health concerns

Published in: BMJ Global Health

Khalil B Ramadi, Shriya Srinivasan, Rifat Atun

Materials and devices for micro-invasive neural interfacing

Published in: MRS Advances

Khalil B Ramadi, Michael J Cima

2018

Focal, remote-controlled, chronic chemical modulation of brain microstructures

Published in: Proceedings of the National Academy of Sciences

Khalil B Ramadi, Canan Dagdeviren, Kevin C Spencer, Pauline Joe, Max Cotler, Erin Rousseau, Carlos Nunez-Lopez, Ann M Graybiel, Robert Langer, Michael J Cima

Design of a precision medication dispenser: preventing overdose by increasing accuracy and precision of dosage

Published in: IEEE Journal of Translational Engineering in Health and Medicine

Shriya S Srinivasan, Sai NR Kantareddy, Ebenezer A Nkwate, Praveen Meka, Ivy Chang, Nevan C Hanumara, Khalil B Ramadi

Miniaturized neural system for chronic, local intracerebral drug delivery

Published in: Science translational medicine

Canan Dagdeviren, Khalil B Ramadi, Pauline Joe, Kevin Spencer, Helen N Schwerdt, Hideki Shimazu, Sebastien Delcasso, Ken-ichi Amemori, Carlos Nunez-Lopez, Ann M Graybiel, Michael J Cima, Robert Langer

2017

Erratum: Characterization of mechanically matched hydrogel coatings to improve the biocompatibility of neural implants

Published in: Scientific reports

Kevin C Spencer, Jay C Sy, Khalil B Ramadi, Ann M Graybiel, Robert Langer, Michael J Cima

The IL-6/STAT3 signaling pathway is an early target of manuka honey-induced suppression of human breast cancer cells

Published in: Frontiers in oncology

Priyanka Aryappalli, Sarah S Al-Qubaisi, Samir Attoub, Junu A George, Kholoud Arafat, Khalil B Ramadi, Yassir A Mohamed, Mezoon M Al-Dhaheri, Ashraf Al-Sbiei, Maria J Fernandez-Cabezudo, Basel K Al-Ramadi

Characterization of mechanically matched hydrogel coatings to improve the biocompatibility of neural implants

Published in: Scientific reports

Kevin C Spencer, Jay C Sy, Khalil B Ramadi, Ann M Graybiel, Robert Langer, Michael J Cima

2016

Acute systemic exposure to silver-based nanoparticles induces hepatotoxicity and NLRP3-dependent inflammation

Published in: Nanotoxicology

Khalil B Ramadi, Yassir A Mohamed, Ashraf Al-Sbiei, Saeeda Almarzooqi, Ghada Bashir, Aisha Al Dhanhani, Dhanya Sarawathiamma, Shahnaz Qadri, Javed Yasin, Abderrahim Nemmar, Maria J Fernandez-Cabezudo, Yousef Haik, Basel K Al-Ramadi

The IL-6/STAT3 signaling pathway is an early target of manuka honey-induced suppression of human breast cancer cells

Published in: Frontiers in oncology

Characterization of mechanically matched hydrogel coatings to improve the biocompatibility of neural implants

Published in: Scientific reports

Kevin C Spencer, Jay C Sy, Khalil B Ramadi, Ann M Graybiel, Robert Langer, Michael J Cima